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Macrophage il-10 blocks cd8+ T cell-dependent responses to chemotherapy by suppressing il-12 expression in intratumoral dendritic cells

Contraindication screening : Tirzepatide is contraindicated in personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, and in patients with severe hypersensitivity to tirzepatide

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Istanbul, Turkey) was administered intraperitoneally (i.p.) at a dose of 45 mg/kg20 to the respective animal groups on day-7 of the experimental protocol